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Treat the underlying disorder The most common medications are oral contraceptives (OCPs), GnRH analogs, and antiandrogens (first-line spironolactone, second-line flutamide, finasteride) Ovarian tumor: surgical removal PCOS: combination OCPs CAH: continuous corticosteroid replacement Adrenal tumor: surgical removal Idiopathic hirsutism: spironolactone

They suppress LH stimulation of the theca cells and they increase sex hormone-binding globulin (SHBG) (thus decreasing free testosterone) It is an androgen receptor blocker and it suppresses 5 -reductase in hair follicles

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The vast majority of games in the industry are evolved from earlier games Their creative, and often their technical, content what you might call their genetic material is a mixture of ideas that have gone before Certain groups of characteristics are especially popular with the players, so games have evolved into different breeds the genres I talked about in 3

class three_d { public: int x, y, z; // 3-D coordinates three_d(int a, int b, int c) { x = a; y = b; z = c; } };

Polycystic Ovarian Syndrome (Stein-Leventhal Syndrome)

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Describe polycystic ovarian syndrome (PCOS) It is the most common chronic endocrine condition characterized by persistent anovulation which leads to secondary amenorrhea and other menstrual irregularities, and androgen excess which may cause hirsutism and virilization It is a dysfunction of the hypothalamic-pituitary axis Increased pulsatile secretions of GnRH excess production of LH excess production and secretion of androgens virilization Some of the excess androgens are converted to estrogen High estrogen levels increase LH (by blocking the inhibitory feedback mechanism of progesterone on the pituitary) High LH levels stimulate the immature follicles to produce more androgens, which then become converted to estrogen The cycle then repeats

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